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Universitätsklinikum Würzburg 

ZIM (Zentrum Innere Medizin)
Haus A3/A4 

Oberdürrbacherstr. 6

97080 Würzburg

ZOM / ZIM

Studien - Virushepatitis

Hepatitis B

REALM: Randomized, Observational Study of Entecavir to Assess Long-term Outcomes Associated with Nucleoside/Nucleotide Monotherapy for Patients with Chronic HBV Infection.
Phase IV
Period: 2007-2016

EudraCT-Nr.: 2005-003284-22

PADD-ON: A prospective, randomised, open-label phase IIb clinical trial assessing the effect of pegylated Interferon alfa-2a (Pegasys®) 180 µg once weekly for 48 weeks in addition to an ongoing nucelos(t)id based treatment on quantitative HBsAg levels in patients with chronic HBeAg-negative hepatitis B.
EudraCT-Nr.: 2011-002812-10

Heparc-2002: A Multicenter, Randomized, Double-blind, Placebo-controlled, Multi-dose Study to Determine the Depth of Hepatitis B Surface Antigen (HBsAg) Reduction Following Intravenous ARC-520 in Combination with Entecavir or Tenofovir in Patients with HBeAg Negative, Chronic Hepatitis B Virus (HBV) Infection.
Period: 2015-2016

EudraCT-Nr.: 2014-004145-27

Heparc-2003: A Multicenter, Randomized, Double-blind, Placebo-controlled, Multi-dose Study to Determine the Depth of Hepatitis B Surface Antigen (HBsAg) Reduction Following Intravenous ARC-520 in Combination with Entecavir or Tenofovir in Patients with HBeAg Positive, Chronic Hepatitis B Virus (HBV) Infection.
Period: 2015-2016

EudraCT-Nr.: 2014-004751-31

STOP-NUC: A multicentre randomized controlled trial evaluating the rate of sustained remission and the safety when stopping nucleos(t)ide analogue treatment in non-cirrhotic HBeAg-negative chronic Hepatitis B patients with long-term virologic response.
Period: 2015-2017

EudraCT-Nr.: 2013-004882-15
 

Hepatitis C

The HepNet Acute HCV IV Study: Interferon-free treatment of Acute Genotype 1 Hepatitis C Virus Infection with Ledipasvir/Sofosbuvir Fixed Dose Combination.
Period: 2015-2016

EudraCT-Nr.: 2013-001081-42

MK-5172-017: A Long-Term Follow-up Study to Evaluate the Durability of Virologic Response and/or Viral Resistance Patterns of Subjects With Chronic Hepatitis C Who Have Been Previously Treated with MK-5172 in a Prior Clinical Trial.
Period: 2015-2016

EudraCT-Nr.: 2012-002232-85

MK-3682-011: A Phase II, Randomized, Open-Label Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172 and MK-3682 with Either MK-8742 or MK-8408 Subjects with Chronic HCV GT1 andGT2 Infection.
Period: 2015-2016

EudraCT-Nr.: 2014-003304-73

Deutsches Hepatitis C-Register – Efficacy and treatment of chronic hepatitis C treatment.
Period: 2014-2020

NIS-Studien-Nr. 2493

Hepatitis C / HIV

TURQUOISE-I: A Multipart, open-label Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir With and Without Dasabuvir Coadministered With and Without Ritonavir in Adults with Genotype 1 or 4 Chronic Hepatitis C Virus Infection and Human Immunodeficiency Virus, Type 1 Coinfection.
Period: 2015-2016

EudraCT-Nr.: 2012-005143-24